Leaders: Jean-Christophe Andrau, Dom Helmlinger, Mounia Lagha
Inaugural Symposium was held on March 17th, 2026
The Genome Dynamics and RNA biology axis explores a wide range of topics, including DNA replication, genome topology and secondary structures of DNA, transcription regulation, chromatin dynamics, RNA biogenesis, and translation.
We use diverse approaches, from genetics, molecular and cell biology, and developmental biology to functional and evolutionary genomics, quantitative imaging, computational biology, and mathematical modeling, in a variety of experimental systems, such as bacteria, yeasts, sea squirts, fruit flies, zebrafish, as well as mammalian cell lines, embryos, and tissues.
Our teams investigate fundamental biological questions related to development, genomic imprinting, sex chromosome compensation, genotype-phenotype relationships, and speciation.
At the forefront of both conceptual and technological innovation, our overarching goal is to understand how genome regulation drives normal development and disease states in cells and organisms, as well as the evolutionary trajectory of model species.
Teams involved: Jean-Christophe Andrau, Anne Blangy & Cécile Gauthier-Rouvière, Maud Borensztein, Konstantin Brodolin, Julie Carnesecchi, Robert Feil, Thierry Forné, Dom Helmlinger, Mounia Lagha, Patrick Lemaire, Domenico Libri & Odil Porrua, Delphine Muriaux & Cyril Favard, Etienne Schwob, Eric Soler, Albert Tsai.
External Seminars organized by the axis “Genome Dynamics & RNA Biology”
